Oral clonidine in the management of acquired opioid dependency.
نویسنده
چکیده
Clonidine is a nonnarcotic analgesic historically used as a nasal decongestant and more recently established as an antihypertensive agent in adults. Because of its sedative properties with few adverse effects, clonidine has also been reported to be an effective pharmacologic agent for the treatment of neonatal abstinence syndrome (NAS). The use of oral clonidine as a primary or secondary agent in the treatment of NAS has been found to reduce hospitalization and duration of treatment in this population.
منابع مشابه
Intravenous clonidine use in a neonate experiencing opioid-induced myoclonus.
USE of clonidine in the management of pain and opioid taper is well-established for adults. Various treatment modalities have been described, ranging from abrupt opioid cessation with clonidine substitution to gradual taper with clonidine as an adjunct. Oral administration of clonidine in neonatal abstinence syndrome has been cited as safe and effective. Short-term use of intravenous clonidine ...
متن کاملImpact of Oral Clonidine on Duration of Opioid and Benzodiazepine Use in Mechanically Ventilated Children: A Randomized, Double-Blind, Placebo-Controlled Study
Objective: Long term use of opioids and benzodiazepines are associated with important untoward effects. The α2 adrenergic agonist clonidine has sedative effects. Our goal was to study clonidine addition to total doses of fentanyl and midazolam and duration of ventilation in pediatric ICU (PICU). Methods: This randomized, double-blind, placebo-controlled trial was conducted in PICU of Mofi...
متن کاملImpact of Oral Clonidine on Duration of Opioid and Benzodiazepine Use in Mechanically Ventilated Children: A Randomized, Double-Blind, Placebo-Controlled Study
Objective: Long term use of opioids and benzodiazepines are associated with important untoward effects. The α2 adrenergic agonist clonidine has sedative effects. Our goal was to study clonidine addition to total doses of fentanyl and midazolam and duration of ventilation in pediatric ICU (PICU). Methods: This randomized, double-blind, placebo-controlled trial was conducted in PICU of Mofi...
متن کاملEffect of Spinal and Systemic Clonidine Administration on the Postoperative Analgesia in Morphine-dependent and Naive Rats
Post operative pain and its control remains one of the most important issues in the field of surgery and health care system. Formalin test has been used as a method for assessing pain and analgesia in rats. Systemic and spinally administered clonidine, an ?2-adrenergic agonist, is proved to enhance postoperative analgesia. It has also been shown that morphine-dependent rats experience more chr...
متن کاملبا کلوفن وکلونیدین در سم‌زدایی مواد افیونی
Abstract Objectives: This study was conducted to evaluate the efficacy and side effects of baclofen and clonidine treatments in opioid detoxification. Method: 66 subjects from an outpatient setting diagnosed with opium dependency (based on DSM-IV) took part in a double blind study. Randomly 32 and 34 subjects were assigned to take respectively baclofen and clonidine for 14 days. Findings: Both ...
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عنوان ژورنال:
- Neonatal network : NN
دوره 32 6 شماره
صفحات -
تاریخ انتشار 2013